Well, Alex mentioned a few days ago that Thieves in the Ninth House is progressing between revisions and approvals.
I take that to be a good sign that it is close*.
I haven't seen any forum announcements (formal or informal) on the Alloy of Law or Secrets of Scadrial supplements mentioned in the Mistborn Adventure Game, but I also wouldn't be too surprised if Pat and Alex have something planned for the Mistborn Adventure Game right around the corner. They've become (understandably) rather tight-lipped on release dates after dealing with the delays surrounding the Mistborn Adventure Game. For example, just look at the new Call to Arms Wave 4 they just put up for sale for Fantasy Craft. They slip a few images out to tease the fans for a couple of days and then WHAM-MO! New content!
I like the thought of porting Brandon's other works over and having a crazy crossover event, but I don't remember if any of the other posters have already started on it or not.
Your comment has summoned to my mind the idea of using the game in a high school teen drama sort of way. Hear me out! Physique is the realm of the jocks, Charm for the preps/socialites, and Wits for the nerds. Resources might need some tweaking to represent a parent's money or the ability to acquire goods at school, but Influence could likely remain unchanged. I think I'm feeling a little bit goofy, but what if we change Spirit to School Spirit? A few more reskins and we have the Lord Ruler as Principal, Houses represented by teachers, and Obligators as hall monitors, snitches, and teacher's pets. Steel Inquisitors? Vice Principal, maybe? At least, "Enforcer" seemed to be in the job description of the VP at the high school I attended. Keepers can potentially be tutors (from that dangerous, free-thinking university in the next city over) or student aides, depending on age.
So, given that, what would the Crew be? Both family and childhood friends work as reasons for the Crew to be together, but they would need some way to deal with the social stratification presented by cliques, and might require a bit more solo time if they can't be "seen together" at school. Motivation could be tricky. That said, I've seen more than a couple of movies about teenagers discovering some terrible secret about their principal and the shenanigans they participate in to oust the evil authority figure; they even cross the established social boundaries to do so, if I'm remembering right.
Of course, I would be sorely tempted to set it in space...and add ninjas...
*For certain definitions of close.