A couple of things I was considering for a more epic style game:
Remove most caps. Most of the stuff that has a limit of x/combat is going to be as often as you want. I'm still probably going to keep timers in place for the really damaging abilities, but things like Shield Block, Contempt, various tricks in the Melee chain will just be "have at it".
Modify Parry / Shield block. These got zero use at my table, because the players found them almost pointless (AC vs Saves were such a vast difference that they'd fail almost every time). I'm not sure where I'll go to with them, but I'm probably also going to add a note to Total Defence where it's dodge bonus also applies to parry / block, and you can make multiple attemps at either when going Total Defence.
(Somewhat) Deadly Combat. Basically Deadly Combat, except it only applies to Standard NPCs. (Not sure about this one TBH).
I've also come up with some setting dependant magic items that heartily smash the magic item rules apart. But most of the stupidly powerful ones will be either macguffins, or temporary prizes (by their nature) - the rest will be balanced, but just break the rules a little bit.
I also agree with Mr A - I think a definition of "Epic Fantasy" needs to be established here.