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I think Black-and-White, Revolving Door and Soap would work well... <snip>
Hmmm. While Soap is a given (I mean, come on, it's high school), I'm not so sure that Black-and-White and Revolving Door would fit the OP's game. For one thing, mysteries require some form of ambiguity to retain the... well, mystery. Not to mention High School is very often the place where childhood naivety starts giving way to harsh reality. In fact, Tense would be a very good quality to use to represent this transition that many people go through trying to cope with the new world called adulthood.
Or, if you prefer a less serious game (with the inspirations being Scooby Doo and Josie & the Pussycats, this is likely) try Comedy Of Errors, since many teens are trying to get used to their new skin, so to speak.
As for Revolving Door, it might be a bad idea for a number of reasons, the key problem being that PCs would be more likely to get into fights.
"I'm gonna be revived after this anyway, so
here we go!"
To solve this problem, I would like to suggest a few things:
1.) Remind your PCs that they are civilians, and killing
anyone means that a high-level SWAT team is going to mug them almost immediately.
2.) While death would be a bit harsh for this type of story, make "incapacitation" actually mean something besides the body disappears to reappear later fully healed. A house rule combining Bang, Your Dead! and No I'm Not! might be an idea. Basically "Either you lug his body to the nearest hospital
now, or you roll a new character, and
this one returns as a hostile NPC. Why would he be hostile? You just left him for dead in a place where there might be monsters! Who wouldn't be hostile after that?!"
However, if they do end up in a "last resort" situation, a combination of Fragile and Bulletproof might be wise. That way the PCs wouldn't have as much room for error, but still have a chance to recover afterwards.
Finally, with the focus being on skills, and considering that during High School, most students are often forced to learn as much as possible in a number of fields of study, Jack Of All Trades will help, especially for those PCs whom insist on more physical characters.