It saddens me to report that I succumbed to evil and watched this film. It was too dark to follow the action, the action was too lame to bother following, and it generally made me weep inside with sadness over how low the mighty have fallen.
It did occur to me about halfway through that what the movie really needed was a Predator hunting *party* rather than just the one dude. There was all manner of potential to make this AVP a pantomime version of CSI: Predator, building off the sequence where the lone hunter checks out the dead Predator's helmet-recorder. The hunting party could have done quite a bit more looking and analyzing, which would have gone a long way toward explaining what the FUCK was up with the hybrids ability to do, y'know, whatever the script needed.
Besides, the human characters were so thinly sketched that this totally should have been a Predators-as-"heroes" movie.
Of course, barring that, nearly any Dark Horse comic script would have been better than this steaming pile (as has been said).
And for NezMaster's benefit, I will state that it would have been better if it had a monkey in it.

So, like Gentry, I decided to watch it, one more time, on DVD, thinking I might have been too fanboi'd up and let my own bias reflect my disappointment. I'm happy to say, nope. This movie was one of the worst films on the face of the planet. ...ever. This thing I would put toe to toe with The Adventures of Pluto Nash, and I'm pretty sure Pluto Nash would be more enjoyable to watch. ...at least Murphy has one good joke in Pluto Nash, AvP2 has no redeeming features..
...Wait! No! It does. It ends. That's the one saving grace. The movie actually does have a credit roll and doesn't just make you watch it time after time for the rest of your hellish existance.